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Title: Split Versus Non-Split Morning Dosing Regimen for Assessment of Quality of Bowel Preparation for Colonoscopy
Authors: Yadav, Bhuwneshwer
Basnet, Bhupendra Kumar
Paudel, Bidhan Nidhi
Shrestha, Ramila
Khanal, Ajit
Poudel, Nandu Silwal
Shah, Manoj
Thapa, Jeewan
Baral, Shankar
Citation: YadavB., BasnetB. K., PaudelB. N., ShresthaR., KhanalA., Silwal PoudelN., ShahM., ThapaJ., & BaralS. (2021). Split Versus Non-Split Morning Dosing Regimen for Assessment of Quality of Bowel Preparation for Colonoscopy. Journal of Nepal Health Research Council, 19(2), 362-366.
Issue Date: 2021
Publisher: Nepal Health Research Council
Article Type: Original Article
Keywords: Boston bowel preparation scale
bowel preparation
split dosage preparation
Series/Report no.: Apr-June, 2021;3509
Abstract: Abstract Background: Different bowel preparation regimens are available. Currently we are giving the entire preparation on the day of colonoscopy. Multiple studies have shown splitting the regimen might improve the quality of bowel preparation with lesser side effects and better compliance. The study was done to compare the efficacy and tolerability of split bowel preparation regimen with non-split dosing regimen. Methods: Single centered observational comparative study was done in a tertiary care hospital. One hundred ninety eight patients requiring elective colonoscopy were assigned to receive one of the two preparations (split versus morning) prior to colonoscopy. Main outcomes were bowel preparation quality and patient compliance and tolerability. Results: There was no significant difference between the two regimen for the mean total Boston Bowel Preparation Scale (6.79VS 6.74,P value -0.777).Patient compliance was better for split dosing compared to single dosing (99 vs 5 p value-<0.001).There were more side effects in the single dosage compared to split dosing except for sleep disturbance which was more in split dosing. Conclusions: The study found that split-dose and single dose polyethylene glycol solution for bowel preparation before colonoscopy had similar efficacy in the quality of bowel preparation. Split-dose polyethylene glycol appears to be superior to single-dose PEG for patient compliance and side effects. Keywords: Boston bowel preparation scale; bowel preparation; colonoscopy; split dosage preparation
Description: Original Article
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 19 No. 2 (2021): Vol 19 No 2 Issue 51 Apr-Jun 2021

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