Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14356/1445
Title: Prevalence of Pseudomonas aeruginosa and its Antibiotic Sensitivity Pattern
Authors: Pokharel, Khilasa
Dawadi, Bishwa Raj
Bhatt, Chandra Prakash
Gupte, Satish
Citation: PokharelK., DawadiB. R., BhattC. P., & GupteS. (2019). Prevalence of Pseudomonas aeruginosa and its Antibiotic Sensitivity Pattern. Journal of Nepal Health Research Council, 17(01), 109-113. https://doi.org/10.33314/jnhrc.v17i01.1877
Issue Date: 2019
Publisher: Nepal Health Research Council
Keywords: Antibiotic resistance
Clinical isolates
Pseudomonas aeruginosa
Series/Report no.: Jan-March, 2019;1877
Abstract: Abstract Background: Pseudomonas aeruginosa is an opportunistic pathogen which causes most of the chronic infection in humans. This study was undertaken to determine the prevalence rate of Pseudomonas aeruginosa that is isolated from various clinical specimens along with its antibiotic susceptibility pattern. Methods: This descriptive cross sectional study was conducted in Kathmandu Medical College and Teaching Hospital (KMCTH) from February to May 2018. Pseudomonas aeruginosa isolated from various clinical specimens were processed in clinical laboratory, Department of Microbiology, KMCTH. Isolation, identification and sensitivity of Pseudomonas aeruginosa to antibiotics were measured. Results: A total of 7527 samples were been processed of which 46 isolates of Pseudomonas aeruginosa were obtained. Pseudomonas aeruginosa was isolated mainly from Pus, Wound swab, Sputum and Tracheal aspirate. Here 63.04% Pseudomonas aeruginosa isolates were resistant to Ceftazidime, 65.21% to Cefixime, 56.52% to Ceftriaxone and Cefotaxime followed by 56.52% to Piperacillin. Furthermore, the current study reveals antibiotics like Imipenem, Meropenem, Piperacillin/Tazobactam, Ciprofloxacin, Gentamicin, Amikacin and Tobramycin were found to be good choice for the treatment of infection caused by this organism. Conclusions: Continuous monitoring of antibiotic susceptibility pattern of Pseudomonas aeruginosa is essential and rational treatment regimens prescription by the clinicians is required to limit the spread of antimicrobial resistance. Keywords: Antibiotic resistance; clinical isolates; Pseudomonas aeruginosa.
Description: Original Article
URI: http://103.69.126.140:8080/handle/20.500.14356/1445
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 17 No. 1 Issue 42 Jan - Mar 2019

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