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Title: Gene-Xpert: Diagnosis of Pulmonary Tuberculosis in a Sputum Smear Negative Patient
Authors: Pandey, Oshna
Paudyal, Buddhi
Basnyat, Buddha
Citation: PandeyO., PaudyalB., & BasnyatB. (2019). Gene-Xpert: Diagnosis of Pulmonary Tuberculosis in a Sputum Smear Negative Patient. Journal of Nepal Health Research Council, 17(01), 125-127.
Issue Date: 2019
Publisher: Nepal Health Research Council
Keywords: Gene-Xpert
Pulmonary tuberculosis
Sputum microscopy
Series/Report no.: Jan-March, 2019;2013
Abstract: Abstract This case report has tried to highlight the ease and benefit of Gene-Xpert testing in difficult to diagnose patient with sputum smear negative pulmonary tuberculosis. Early treatment of tuberculosis is usually delayed by lack of rapid and accurate diagnostic modalities, especially in resource-limited settings like ours. Gene-Xpert is a rapid test based on real time PCR assay and molecular technology for the detection of Mycobacterium tuberculosis. It is highly sensitive tool and enables simultaneous detection of rifampicin resistance within short period of time i,e. <2hrs. It has distinct advantage of providing same-day diagnosis which could potentially limit loss to follow up during diagnostic evaluation of smear negative tuberculosis patients. Keywords: Gene-Xpert; pulmonary tuberculosis; sputum microscopy.
Description: Case Report
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 17 No. 1 Issue 42 Jan - Mar 2019

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