Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14356/1618
Title: Nasal Carriage Rate of Methicillin Resistant Staphylococcus aureus among Health Care Workers at a Tertiary Care Hospital in Kathmandu, Nepal
Authors: Khatri, Sabita
Pant, Narayan Dutt
Bhandari, Raju
Shrestha, Krishma Laxmi
Shrestha, Chandrika D
Adhikari, Nabaraj
Poudel, Asia Poudel
Citation: KhatriS., PantN. D., BhandariR., ShresthaK. L., ShresthaC. D., AdhikariN., & PoudelA. (2017). Nasal Carriage Rate of Methicillin Resistant Staphylococcus aureus among Health Care Workers at a Tertiary Care Hospital in Kathmandu, Nepal. Journal of Nepal Health Research Council, 15(1). https://doi.org/10.33314/jnhrc.v15i1.967
Issue Date: 2017
Publisher: Nepal Health Research Council
Keywords: Health care workers
MRSA
Nasal carriage
Nepal
Staphylococcus aureus
Series/Report no.: Jan-April, 2017;967
Abstract: Abstract Background: Methicillin-resistant Staphylococcus aureus is one of the most common causes of nosocomial infections. Due to its multidrug resistant nature; infections due to Methicillin-resistant Staphylococcus aureus are often very difficult to treat. Colonized health care workers are the important sources of Methicillin-resistant Staphylococcus aureus. The objectives of this study were to determine the nasal carriage rate of Methicillin-resistant Staphylococcus aureus among health care workers at Kathmandu Medical College and Teaching Hospital, Nepal and to assess their antimicrobial susceptibility patterns. Methods: A cross sectional study was conducted among 252 health care workers from July to November 2013. Mannitol salt agar was used to culture the nasal swabs. Antimicrobial susceptibility testing was performed by Kirby-Bauer disc diffusion technique following Clinical and Laboratory Standards Institute guidelines. Methicillin-resistant Staphylococcus aureus strains were confirmed by using cefoxitin disc and by determining the minimum inhibitory concentration of oxacillin by agar dilution method. Results: Of 252 healthcare workers, 46(18.3%) were positive for Staphylococcus aureus among which 19(41.3%) were Methicillin-resistant Staphylococcus aureus carriers. Overall rate of nasal carriage of Methicillin-resistant Staphylococcus aureus was 7.5% (19/252).The higher percentages of lab personnel were nasal carriers of S. aureus (31.6%) and Methicillin-resistant Staphylococcus aureus (10.5%).The percentages of nasal carriage of S. aureus (35.7%) and Methicillin-resistant Staphylococcus aureus (14.3%) were highest in the health care workers from post operative department. Higher percentage of Methicillin-resistant Staphylococcus aureus were susceptible toward amikacin (100%) and vancomycin (100%) followed by cotrimoxazole (84.2%). Conclusions: High rates of nasal carriage of S. aureus and Methicillin-resistant Staphylococcus aureus were observed among the healthcare workers, which indicate the need of strict infection control measures to be followed to control the nosocomial infections. Keywords: Health care workers; MRSA; nasal carriage; Nepal; Staphylococcus aureus.
Description: Original Article
URI: http://103.69.126.140:8080/handle/20.500.14356/1618
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 15 No. 1 Issue 35 Jan-Apr 2017

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