DSpace Community: JNHRC

Free Basic Healthcare in Nepal: Can the Dream be Turned into Reality in the Pursuit of Universal Health Coverage?

Sun, 01 Jan 2023 00:00:00 GMT

Title: Free Basic Healthcare in Nepal: Can the Dream be Turned into Reality in the Pursuit of Universal Health Coverage? Authors: Aryal, Krishna K Abstract: NA Description: Editorial

Guillain Barre Syndrome after vaccination against Corona Virus Disease19: Managed in limited resource setting

Sat, 01 Jan 2022 00:00:00 GMT

Title: Guillain Barre Syndrome after vaccination against Corona Virus Disease19: Managed in limited resource setting Authors: Kamar, Sher Bahadur; Bhatta, Uttam Kumar; Singh, Ratna; Timilsana, Manju Paudel Abstract: Abstract A 16-year-old boy who classically featured Guillain Barre Syndrome (GBS) after Corona Virus Disease-19 vaccination was timely treated successfully in limited resource setting in far western province. After Moderna (mRNA COVID 19 Vaccine) vaccination, he rapidly developed ascending paralysis of limbs without autonomic and sensory or cranial nerve involvement. He has been treated with Intravenous Immuno-Globulin (IVIG). Over six-weeks long observation and supportive care and he was discharged with full recovery. Many GBS cases after vaccination have been reported but yet to know the association of vaccine. It is very important to address the complication for successful vaccination programme. Keywords: Complication; COVID-19; guillain barre syndrome; vaccine Description: Case Report

Genodermatoses Picture: Difficulties Faced And Way Forward in Nepal

Sat, 01 Jan 2022 00:00:00 GMT

Title: Genodermatoses Picture: Difficulties Faced And Way Forward in Nepal Authors: Parajuli, Niraj; Baskota, Rabindra; Jain, Ritu Abstract: Abstract Genodermatoses are group of genetic disorders that present with cutaneous manifestations. The exact prevalence on many of these conditions are unknown due to its rarity, need of specialized tests for diagnosis and lack of proper reporting system. Most of the patients are faced with life-long disability and associated stigma. There is a need for specialized centers for proper diagnosis of these conditions and a very elaborated yet simple reporting system in Nepal. These rare conditions should be kept in priority by the government in align with the sustainable development goals to ensure healthy-lives and promote well-being for all. A wider engagement of patient-led support groups might be useful in providing necessary information on the disease to the general population and alleviate the stigma associated with these diseases. Keywords: Epidermolysis bullosa; genodermatoses; rare diseases; Nepal Description: Short Communication

Dyslipidemia and Thyroid Dysfunction Associated with Psoriasis

Sat, 01 Jan 2022 00:00:00 GMT

Title: Dyslipidemia and Thyroid Dysfunction Associated with Psoriasis Authors: Rizal, Shikha; Joshi, Bishal Raj; Jha, Sanjay Kumar; Pradhan, Manish; Regmi, Sunil Abstract: Abstract Background: Psoriasis is a T-cell mediated inflammatory skin disorder which causes considerable psychosocial disability resulting in major impact on patient’s quality of life. The dominant response of Th1 cells and the high expression of related inflammatory factors appears in both psoriasis and thyroid dysfunction. Psoriasis can lead to increased risk of incidence of cardiovascular events for which dyslipidemia is an important risk factor. This study aims to evaluate thyroid function and lipid profile and its association in patients with psoriasis. Methods: This was a prospective case-control study conducted at the Department of Biochemistry, Nobel Medical College Teaching Hospital from November 2021 to October 2022. Seventy six clinically diagnosed psoriatic patients were taken as case and eighty non-psoriatic patients coming for other skin lesions were included in the study as control. Thyroid function test (serum free T3, T4, TSH) and lipid profile (total cholesterol, low density lipoprotein, high density lipoprotein and triglyceride) were done. Results: Hypothyroidism was most common thyroid abnormalities in our study population which was 13.15% (n=10). The lipid profile parameters were significantly higher in the psoriatic patients than in the controls (p<0.001). The odds of psoriatic patient having thyroid dysfunction was 2.8 times higher compared to other non-psoriatic patients and the odds of psoriatic patient having dyslipidemia was 8.7 times higher compared to other non-psoriatic patients. Conclusions: It is thus useful to assess thyroid function test and lipid profile in patients with psoriasis considering their role in etiopathogenesis and co-morbidity of psoriasis. Keywords: Co-morbidity; dyslipidemia; thyroid dysfunction Description: Original Article