Y-chromosome polymorphism in the Nepalese population

Abstract

Thirty-eight Nepalese blood samples were collected from male donors and DNA was extracted from them by a conventional method (for 36 samples) or by using Agarose plugs (2 samples). Each of the samples was scored for Y - Chromosome polymorphisms with 10 PCRable markers available. Y haplotypes found in Nepal were compared with those found in genetically and geographically distinct parts of the worlds using the data already obtained (1). A Neighbor-joining tree and a Maximum likelihood tree were constructed to assess the results (2). It was found that the Nepalese are genetically closely related to the Indians and the Sri Lankans and two Kirants showed a new of Polymorphism, designed XXIX (3).