Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14356/999
Title: Prevalence of Gestational Diabetes Mellitus in Nepal: A Systematic Review and Meta-analysis
Authors: Pokharel, Pashupati
Pokhrel, Kailash Mani
Lamichhane, Pratik
Rawal, Suniti
Citation: PokharelP., PokhrelK. M., LamichhaneP., KhanalK., & RawalS. (2022). Prevalence of Gestational Diabetes Mellitus in Nepal: A Systematic Review and Meta-analysis. Journal of Nepal Health Research Council, 20(01), 12-20. https://doi.org/10.33314/jnhrc.v20i01.3874
Issue Date: 2022
Publisher: Nepal Health Research Council
Article Type: Review Article
Keywords: Diabetes in pregnancy
Gestational diabetes mellitus
Meta-analysis
Nepal
Prevalence
Series/Report no.: Jan-March, 2022;3874
Abstract: Abstract Background: Gestational diabetes mellitus is a condition of glucose intolerance during pregnancy. The burden of Gestational diabetes mellitus is ever increasing including a lower middle-income country like Nepal. Methods: This meta-analysis was conducted in accordance to the guidance of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Databases of “Embase”, “Google Scholar”, “Scopus”, “Web of Science” were searched for observational studies in Nepal from 2000 to July 2021. Random effect model was used to estimate the pooled prevalence subgroup analysis. Results: This systematic review and meta-analysis analyzed 9 studies with a total of 20865 participants. Pooled prevalence of gestational diabetes mellitus was 2.61% (95% CI: 1.25- 5.37). From subgroup analysis, the prevalence of Gestational diabetes mellitus according to the diagnostic criteria were: International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria 6.56% (95% CI: 4.79-8.92), World Health Organization (WHO) criteria 4.81% (95% CI: 3.79-6.08), Diabetes in Pregnancy Study Group of India (DIPSI) criteria 4.71% (95% CI: 3.06-7.18), Carpenter and Coustan criteria (CC) 1.08% (95% CI: 0.43-2.71); prevalence according to the publication time: before 2015 1.20% (95% CI: 3.64-6.41), in and after 2015 4.84% (95% CI: 0.42-3.39); prevalence according to the place: within Kathmandu valley 2.70% (95% CI: 1.17-6.08), outside Kathmandu valley 2.28% (95% CI: 0.26-17.15). Conclusion: Our study revealed the increasing prevalence of GDM in Nepal. Further large observational studies at local levels are essential to measure the actual burden, risk factors and potential preventive measures for Gestational diabetes mellitus. Keywords: Diabetes in pregnancy; gestational diabetes mellitus; meta-analysis; Nepal; prevalence.
Description: Review Article
URI: http://103.69.126.140:8080/handle/20.500.14356/999
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 20 No. 01 (2022): Issue 54 Jan-March, 2022

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