Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.14356/1547
Title: Barrett’s Esophagus in Patients with Gastroesophageal Reflux Disease
Authors: Dewan, Khus Raj
Patowary, Bhanumati Saikia
Bhattarai, Subash
Shrestha, Gaurav
Citation: DewanK. R., PatowaryB. S., BhattaraiS., & ShresthaG. (2018). Barrett’s Esophagus in Patients with Gastroesophageal Reflux Disease. Journal of Nepal Health Research Council, 16(2), 144-148. https://doi.org/10.33314/jnhrc.v16i2.1568
Issue Date: 2018
Publisher: Nepal Health Research Council
Article Type: Original Article
Keywords: Barrett’s esophagus
Erosive esophagitis
Endoscopy
GERD
Quadrant biopsies
Series/Report no.: Apr-June, 2018;1568
Abstract: Abstract Background: Barrett’s esophagus a is metaplasia of normal squamous cells that line the lower part of the esophagus and carries a major risk for adenocarcinoma of esophagus. In Asian population, the prevalence of Barrett’s esophagus and adenocarcinoma are less common than in Western countries but has been increasing. Methods: This is a hospital based descriptive study comprising of 120 consecutive patients with symptoms of gastroesophagial reflux disease belonging to both sexes of any age group. The diagnosis of gastroesophagial reflux disease was based on the symptoms like heart burn and regurgitation. Upper gastrointestinal endoscopy was done in all the patients. Four quadrant biopsies were taken from the esophagogastric junction in suspected case of Barrett’s esophagus. The diagnosis of Barrett’s esophagus was confirmed histopathologically. Results: There were 44.2% males and 55.8% females, age ranging from 22 to 85 years mean being 44.33+13.37. Of them, gastroesophagial reflux disease was mild in 54.16%, moderate in 21.16% and severe in 16.66%. Upper Gastrointestinal endoscopy revealed non erosive gastroesophagial reflux disease in 50%, erosive in 45%, hiatal hernias in 5% and Barrett’s esophagus in 1.6%. Both patients with Barrett’s esophagus were elderly and had short segment (<3cm) involvement with no evidence of dysplasia or adenocarcinoma histopathologically. Conclusions: Endoscopic surveillance with detailed inspection and systematic biopsies is recommended for most patients with Barrett’s esophagus. Esophageal carcinoma if detected should be treated at the earliest. Keywords: Barrett’s esophagus; erosive esophagitis; endoscopy; GERD; quadrant biopsies.
Description: Original Article
URI: http://103.69.126.140:8080/handle/20.500.14356/1547
ISSN: Print ISSN: 1727-5482; Online ISSN: 1999-6217
Appears in Collections:Vol. 16 No. 2 Issue 39 Apr-Jun 2018

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